Grinding Chinese Medicine - Pharmaceutical Application

Description：After Chinese medicines are grind and crushed into fine powder increasing the surface area. Grinding processes eases the preparation of medicines, where coarse powders can be consumed in the powder form, and finer powders can be processed into pills. A common Chinese medicinal process requires measuring precise dosages before the addition of honey to the manufacture of pills. Over the years, the grinding process became an important basis for the administration of pharmaceutical drugs.

According to Fick’s law of diffusion, the increase in surface area facilitates the extraction of the active ingredients through diffusion. The increased surface area makes the ingredients more soluble in solvents, allowing for better absorption. Through ongoing medical studies, ultra-fine grinding of herbal ingredients increases the dissolution rate, reduces the required dosage, increases bio-availability and brings enhanced pharmacological effects. Superfine medicinal powders, with their large surface area, greatly improves the absorption rate and degree of absorption of the active ingredients at the time of administration achieves quick, efficient and long lasting treatment benefits.

 

Ultra-fine Chinese Medicine Grinding Applications：The grinding process in Chinese medicine aims to break the ingredients to the cellular level, and to destroy the cells. As most of the herbal and medicinal ingredients are found within the cells, the grinding operation is commonly called "cellular level grinding process", with the obtained ingredients "inner-cellular obtained Chinese medicinal powdered ingredients", commonly referred to as "Chinese powdered medicine". The current grinding processes in Chinese medicinal applications aims to destroy the cells to release the substances within the cells instead of achieving powder fineness. However, grinding to a macro level causes many cells to remain intact, reducing the expression of the medicinal contents.

Through ultra-fine grinding processes, the grinding size efficiency of the cells increases from 75-100 microns to below 50 microns, hence increasing the breaking of cells by approximately 95%. With better cell destruction, more inner-cellular contents can be released, improving the yield of medicinal contents. After microscopic inspection, only very few cells are left intact after the grinding process.

 

Common Traditional Chinese Medicine Powders：Angelica Sinensis, Green Tea, West Olive, Salvia, Fungus Spores, Fungus Powder, Cordyceps Sinensis, Terminalia Chebula Retz, Panax, Acanthopanax, Ding Xin Grass, Konjac Flour, Panax Notoginseng, Mushrooms, Ginseng, Sheep Placenta, Pine Pollen, Bee Pollen, Chitin, Arrowroot, Taro, Licorice Powder, Jujube Carbon, Chinese Wolfberry, Bitter Gourd, Deer Bone, Ginkgo Biloba, etc.

 

Chinese Medicinal Size Reduction Processes：Chinese medicinal production uses ultra-fine grinding (for non-fiber, non-sugar class of drugs), vibration grinding (applicable for fiber-type drugs), jet milling (for drug ultra-fine grinding) and cryogenic grinding (applicable to grinding heat sensitive drugs).
 

 

 

                           

                                     FQP03 Disk Jet Mill                                                                          FQP01Disk Jet Mill

Working Principle：

The FQP series disk jet mill utilizes highly pressurized air that is cooled, filtered and dried before entering the rotary grinding chamber to produce powders. The feed enters the grinding chamber through an inlet nozzle to multiple high-speed rotating disks, causing the feed to undergo size reduction through collision, friction, shearing and crushing forces to produce powders with superfine structure and morphology.

After grinding, the superfine powders will be carried along with the pressurized gas to enter a precise grading and classifying section within the FCP jet mill to sort the various sizes of powders. After purification and screening, the powders are produced through the outlet.

 

Product Highlights and Advantages：

FQP series jet mills uses an air classifying technology that enables the continuous grinding of materials, resulting in a high volume.

1. By controlling of the grinding factor, the sizes of the powders can be adjusted.

2. Different equipment configurations can be adopted for materials with different properties and requirements.

3. Easy to open structure to allow ease of cleaning maintenance and replacement of parts.

4. Advanced machinery control chip installed to precise operation, saving manpower and resources.

5. Well finished surface with no dead ends to ease cleaning maintenance, meeting CMP standards.

 

Model	Compressed Air Consumption m3/min	Production Capacity Kg/h	Compressor Power kw	Feed Size	Outlet Size Range D50: um
FQP02	1.5-2	0.5-5	11-18.5	<250Micron	2~20
FQP03	3	2-20	22	<420Micron	2~20
FQP06	6	20-100	45	<420Micron	2~20
FQP10	10	50-200	75	<420Micron	2~20
FQP20	20	100-500	132	<8410Micron	2~20
FQP40	40	300-800	250	<841Micron	2~20

 

 

 

 

 

 

 

 

                            

                                                                       FQW Pharmaceutical Jet Mill（GMP）

Working Principle:

The pharmaceutical jet mill uses high speed air to achieve ultra-fine grinding of dry materials, and has various components such as feeders, crushing, grading and sorting zones. Through feeding the material into the crushing zone, the feed undergoes vacuum size reduction with the air flow drawing the crushed powder into the sorting and classification zone. When the material meets the size requirements, the powder will pass and be collected in a cyclone powder collector, while the larger sized and coarse materials returned into the grinding and crushing zone to be further reduced in size.

 

Structural Features

• 1. Well finished equipment without dead ends, easy to clean. Meets CMP standards.
• 2. 25-35% more yield compared to a conventional fluidized bed jet mill for the same grinding fineness.
• 3. Materials are reduced in size through pneumatic means. Does not produce heat in the process.
• 4. Optimized classifying wheel mechanism achieves higher line speed with higher cutting accuracy than the conventional ultra-fine jet mills.
• 5. Consistent and production with a narrow size distribution of the produced powders.
• 6. Through the use of advanced automation and controls with real time operating status display, the equipment is easy to operate.
• 6. Additional control and monitoring systems such as central monitoring systems or remote monitoring can be added as according to the customers’ requirements.

 

Applications

Widely used in grinding to produce ultra-fine medicines, pesticides, chemicals, minerals (metallic and non-metallic), electronics, fire-retardant materials, dry powder, etc.